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ROS-regulated factors (transcription factors, cytokines, and chemokines) are involved in various aspects of cellular and regulate inflammation, immune cell migration, cellular proliferation, survival, and apoptosis.51 ROS-induced activation of signaling molecules such as Src, Ras, PI3K, EGFR, MAPK, (p38MAPK), JNK, and ERK leads to the activation of transcription factors, which in turn trigger the generation of pro-inflammatory cytokines and chemokines