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Complementary approaches include high-frequency nsPEF combined with magneto-poration of iron oxide nanoparticles to suppress A375 cell viability in vitro (68), and integrin-targeted nsPEF IRE (INSPIRE) achieving voltage-dependent tumor reduction in equine spontaneous melanoma (84-88% volume reduction at 2kV) (69)

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Cortisone is not always the wrong choice – for acute inflammatory episodes, it can provide meaningful short-term relief