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Acknowledgements The authors would like to thank the FIOCRUZ-Bahia flow cytometry, histotechnology, and electron microscopy cores for collecting flow cytometric data, performing histological techniques, and acquiring confocal microscopy data, respectively

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Potential therapeutic strategies include inhibiting neutrophil NET formation, regulating neutrophil apoptosis pathways, intervening in TLR9-mediated endoplasmic reticulum stress, and targeting gut microbiota and their metabolites