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Histopathological evaluation of insulin-DMSO formula designed for direct nose-to-brain delivery

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Even though animal models of alcohol liquid diet indicate that nutritional deficiency has little to do with ethanol-induced neurodegeneration (Tajuddin et al., 2014), chronic intermittent access to alcohol (20% v/v in tap water for 26 weeks, 5–6 g/kg intake per session) (Liu et al., 2013)