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The activation of MAPK can activate the downstream “peroxisome proliferators-activated receptor gamma” (PPARγ) to induce the apoptosis of vascular smooth muscle cells (Wan et al., 2014), and inactivation of the MAPK/PPARγ signaling alleviates diabetes-induced ED via suppression of the corpus cavernosal cell apoptosis (Zhang Z

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These fatty acids are essential components of cell membranes, influencing their fluidity and the function of membrane-bound proteins, which are crucial for cellular signaling and function[268]