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Indeed, while in many cases it would be desirable or crucial to specifically target a particular GST isozyme or polymorphic form, this is hardly achievable with the molecules synthesized and investigated so far

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A systematic review included 6 randomized clinical trials between 2002 and 2017, encompassing a total of 908 patients to compare the effects of BMP-2-loaded implants versus autologous iliac crest bone grafts in lumbar spine posterolateral fusion [397]