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Their potential relevance is indirect: because anxiety, rumination, and stress are among the most common drivers of insomnia, a peptide that reliably lowers anxiety could plausibly improve sleep onset and continuity for some people

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Fat accumulation in mGSTA4 null mice parallels tissue levels of 4HNE We generated a mouse lacking mGSTA4-4 (Engle et al., 2004), the sole murine GST with high catalytic efficiency for 4HNE (Zimniak et al., 1994)