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The encoding factors for nuclear genes identified so far are as follows: PGC‐1α, the transcription factor A (TFAM), the uncoupling proteins 2 (UCP2) and the uncoupling proteins 3 (UCP3), 10 (c) mitochondria biogenesis implies a specific route consisting in the recruitment of the novel proteins by the pre‐existing mitochondria, followed by their fragmentation, via fission