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The answer, as is often the case in nuanced science, is: it depends entirely on the objective

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The Neelakantan 2019 Biochemical Pharmacology Paper The 2019 paper by Neelakantan, Brightwell, Graber and colleagues, titled "Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle," is the foundational reference for 5-Amino-1MQ in muscle research