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Data that remained non-normally distributed and/or heteroscedastic after log transformation were analyzed (not log-transformed, but still 1e−13-transformed) with a Kruskal–Wallis test, while normally distributed and homoscedastic data were analyzed with a one-way ANOVA, performed on the log-transformed data as necessary

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This pitfall, in addition to the problem in standardization of the antigenic composition of the cultured parasites and the need of a cold chain for distribution of the vaccine to the field are limiting factors in commercialization of this vaccine (89)