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Moreover, subsets of astrocytes recruited to neuronal circuits under focal demand can episodically undergo cell-state changes, reflected in bursts of transcriptional activity that rapidly re-express gene sets—whether encoding cytoskeletal proteins, transmembrane transporters or antioxidant enzymes—tailored to their microenvironmental stimuli 49,50,51

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it does not replace antiviral therapy in high-risk or severe cases of influenza