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Furthermore, certain erinacines have shown antimicrobial activity, particularly against Helicobacter pylori , suggesting a role in gut health and gastric ulcer prevention [49]

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Astrocytes exposed to EA and 3-morpholinosydnonimine (SIN1, a compound that generates peroxynitrates) show significant increases in lactate dehydrogenase (an indirect marker of cell death), decreased ATP levels and decreased mitochondrial membrane potential