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La administración por sonda en ratas, a concentraciones de 125 y 250 mg/kg de peso corporal (hembras) y 62 y 125 mg/kg de peso corporal (machos), cinco días a la semana durante 113 semanas, produjo en las hembras con la dosificación más alta un ligero aumento de la incidencia de adenocarcinomas de las glándulas mamarias, por encima de los valores habituales

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The egg hatching assay was performed on harvested embryos, and we confirmed the presence of AFAs within treated embryos using NMR (Fig