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The PSA response rate was 76.9%, with a median survival of 35.1 months, which demonstrated beneficial effects compared with the 45% PSA response rate and median survival rate of 17.4 months reported by the TAX-327 trail (109)

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Inhibiting β-Oxidation Alters the Redox Maturation of ER Client Proteins Given the association of GSSG with the oxidative protein folding environment in the ER, we examined whether ET altered the oxidative state of client proteins in the ER lumen