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In enteric hyperoxaluria the high oxalate absorption is often associated with diarrhea-induced volume depletion, metabolic acidosis and hypocitraturia, providing favorable conditions for oxalate accumulation and precipitation in renal tissue [5, 7, 65]

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have found that the monosarbonyl curcumin derivative, DM96, is an effective GSTP1 inhibitor (IC 50 = 5.45 ± 1.08 μM) (Figure 9E), with also showed potent cytotoxicity against prostate cancer cell line DU-145 (IC 50 = 8.60 ± 1.07 μM), therefore was proposed as a decent chemical sensitizer to cancer cells [198]