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Consequently, the paracellular pathway, which is typically tightly regulated, becomes more permeable, allowing neurotoxic substances and other potentially harmful agents to pass through the BBB and enter the brain parenchyma [54,63]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Gojkovic S., Krezic I., Vranes H., Zizek H., Drmic D., Vuletic L.B., Milavic M., Sikiric S., Stilinovic I., Simeon P., et al