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FIGURE 2 3.2 Impact of linezolid and/or vitamin C on antioxidant and oxidative stress parameters As shown in Figure 3, the treatment with linezolid induced a status of oxidative stress represented by significantly (p ≤ 0.05) elevated levels of hepatic and renal NO (76.23 ± 1.677 μmole/g and 95.88 ± 1.065 μmol/g tissue, respectively) versus 44.42 ± 1.054 μmole/g and 55.31 ± 1.56 μmole/g tissue, respectively and lipid peroxidation product, MDA, (65.22 ± 1.116 and 69.51 ± 0.85 nmol/g tissue, respectively) versus 32.76 ± 0.745 nmole/g and 39.15 ± 0.914 nmol/g tissue, respectively