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In the CY 2026 PFS proposed rule (90 FR 32677), we stated that, based on performance year 2023 ACO quality results, among 71 ACOs that qualified for the health equity adjustment in performance year 2023, 13 ACOs earned health equity adjustment bonus points with an average of 3.54 bonus points (out of 10) awarded

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Increased ER stress may be a self-protective signal transcription pathway after mild injury (Xie et al., 2016), In contrast, excessive ER stress triggers extensive neuronal death via CHOP activation