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Linearity and Stability of Intravenous Busulfan Pharmacokinetics and the Role of Glutathione in Busulfan Elimination - Biology of Blood and Marrow Transplantation

When paired with methionine deprivation, both drugs showed enhanced cytotoxicity at much lower doses, suggesting methionine deprivation may be a useful strategy to enhance efficacy and lower toxicity of various anti-cancer drugs [10,150]

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Because these are gradual, natural processes, GHK-Cu doesn't work overnight