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It is well known that DMD is caused by mutations in the dystrophin gene, resulting in progressive muscle damage and degeneration due to destabilisation of the dystrophin-glycoprotein complex (DGC) (a large multicomponent complex responsible for mechanical stability) 2

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Consistently, 3-AT significantly counteracted the CAT’s stimulations on intracellular ROS, LDH release, and MDA, as is shown in Fig