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With respect to the primary aim of the study, NSI-189 was well tolerated supporting the dose escalation up to 40 mg t.i.d

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Research questions may include: How GHK coordinates copper ions Whether copper association changes peptide conformation How the complex behaves in different buffers or matrices Whether free and bound copper can be distinguished analytically How complex composition changes over time Whether GHK and GHK-Cu produce different assay responses How related metal ions affect coordination How degradation alters complex behavior Copper Coordination Research Copper coordination is central to GHK-Cu research