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324,343 In pancreatic and colorectal cancers, intratumoral γ -proteobacteria express a long isoform of cytidine deaminase (CDD-L) that catalyzes the deamination of gemcitabine into its inactive metabolite 2’,2’-difluorodeoxyuridine (dFdU), thereby conferring chemoresistance

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Summer 2009;2(3):159-168