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Unlike the initial claim for generalization of the epithelial stomach protection to other epithelial protection (cytoprotection → organoprotection)[14-16,19], at that time, these studies[14-16,20,21] made no attempt to generalize the findings seen for endothelium recovery in the stomach

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The degenerative process associated with osteoarthritis creates a painful cycle where inflamed synovial tissue produces cytokines and prostaglandins that sensitise nerve endings, while swelling and effusion mechanically restrict movement [2]