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(3) Low efficacy Although the autophagy inducers rapamycin and alginate and the autophagy inhibitor 3-methyladenine (3-MA) have been widely used in animal or cellular disease models (to treat liver diseases, neurodegenerative diseases, etc.) and have shown clear efficacy, they are not used in the clinic because of the high concentrations needed to induce their function [168]
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(Catania et al., 2004) Current Research Limitations Although there has been increased attention towards peptide research, some drawbacks should be pointed out: The lack of any clinical trials conducted in relation to the combination of KLOW Blend The evidence comes from a separate peptide study The possible interactions among peptides are only hypothetical The effectiveness and safety of the combination in humans have not been proven yet
