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Postfixative was removed and cells were washed (five times for 1 min each) with 0.1 M sodium cacodylate buffer pH 7.4 containing 2 mM CaCl 2 on ice and then washed (five times for 1 min each) with cold double-distilled H 2 O (ddH 2 O) on ice

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As scientific capabilities advance, regulatory frameworks will continue to evolve alongside them